Recombinant MBP antibody (AA 150-250)

Catalog No. ABIN7870856

This Rabbit Monoclonal antibody specifically detects MBP in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant MBP antibody (AA 150-250) (ABIN7870856)

Target: MBP (Myelin Basic Protein (MBP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: MBP-4277R

Product Details anti-MBP Antibody

Binding Specificity: AA 150-250

Purpose: Recombinant Myelin Basic Protein Antibody (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: A portion of amino acids 150-250 from the human protein was used as the immunogen for the recombinant Myelin Basic Protein antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant Myelin Basic Protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Myelin Basic Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin Basic Protein

Background: Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas.

UniProt: P02686