Recombinant Prostate Specific Antigen antibody (AA 150-250)

Catalog No. ABIN7870873

The Mouse Monoclonal anti-Prostate Specific Antigen antibody (Clone rKLK3-6947) (ABIN7870873) specifically detects Prostate Specific Antigen in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Prostate Specific Antigen antibody (AA 150-250) (ABIN7870873)

Target: Prostate Specific Antigen (PSA)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RKLK3-6947

Product Details anti-Prostate Specific Antigen Antibody

Binding Specificity: AA 150-250

Purpose: Prostate Specific Antigen Antibody / PSA

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 150-250) from the human protein was used as the immunogen for the Prostate Specific Antigen antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Prostate Specific Antigen antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Prostate Specific Antigen antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: Prostate Specific Antigen

Background: Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This mAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This mAb makes an excellent pair with mAb 1A7G6B6 for PSA tests.

UniProt: P07288

Pathways: Complement System