MAP2 antibody (AA 1500-1700)

Catalog No. ABIN7870969

The Mouse Monoclonal anti-MAP2 antibody (Clone MAP2-7673) (ABIN7870969) specifically detects MAP2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for MAP2 antibody (AA 1500-1700) (ABIN7870969)

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MAP2-7673

Product Details anti-MAP2 Antibody

Binding Specificity: AA 1500-1700

Purpose: MAP2 Antibody / Microtubule-associated protein 2

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1500-1700) from the human protein was used as the immunogen for the MAP2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the MAP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: MAP2

Background: Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubule-associated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance microtubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.

UniProt: P11137