RYK antibody (AA 160-190)

Catalog No. ABIN7871095

The Rabbit Polyclonal anti-RYK antibody (ABIN7871095) specifically detects RYK in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for RYK antibody (AA 160-190) (ABIN7871095)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RYK Antibody

Binding Specificity: AA 160-190

Purpose: RYK Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 160-190 from the human protein were used as the immunogen for the RYK antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the RYK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RYK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: RYK

Background: RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size