IRF1 antibody (AA 170-315)

Catalog No. ABIN7871251

The Rabbit Polyclonal anti-IRF1 antibody (ABIN7871251) specifically detects IRF1 in WB, ELISA, IF, FACS and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for IRF1 antibody (AA 170-315) (ABIN7871251)

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IRF1 Antibody

Binding Specificity: AA 170-315

Purpose: IRF-1 Antibody / Interferon regulatory factor 1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M170-L315) was used as the immunogen for the IRF-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IRF-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IRF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Alternative Name: IRF-1

Background: Interferon regulatory factor 1, also known as MAR is a protein that in humans is encoded by the IRF1 gene. The IRF1 gene is mapped to chromosome 5q31.1 by pulsed-field gel electrophoresis. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy