Prosaposin antibody (AA 182-479)

Catalog No. ABIN7871467

The Rabbit Polyclonal anti-Prosaposin antibody (ABIN7871467) specifically detects Prosaposin in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for Prosaposin antibody (AA 182-479) (ABIN7871467)

Target: Prosaposin (PSAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prosaposin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Prosaposin Antibody

Binding Specificity: AA 182-479

Purpose: Prosaposin Antibody / PSAP

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q182-I479) was used as the immunogen for the Prosaposin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Prosaposin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Prosaposin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Prosaposin

Target: Prosaposin (PSAP)

Alternative Name: Prosaposin

Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity