GLIS3 antibody (AA 184-765)

Catalog No. ABIN7871482

The Rabbit Polyclonal anti-GLIS3 antibody (ABIN7871482) specifically detects GLIS3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLIS3 antibody (AA 184-765) (ABIN7871482)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GLIS3 Antibody

Binding Specificity: AA 184-765

Purpose: GLIS3 Antibody / GLI-similar 3 / ZNF515

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A184-P765) was used as the immunogen for the GLIS3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GLIS3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GLIS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS3

Background: Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene. This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

UniProt: Q8NEA6