FKBP15 antibody (AA 19-1210)

Catalog No. ABIN7871554

The Rabbit Polyclonal anti-FKBP15 antibody (ABIN7871554) specifically detects FKBP15 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FKBP15 antibody (AA 19-1210) (ABIN7871554)

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-FKBP15 Antibody

Binding Specificity: AA 19-1210

Purpose: FKBP15 Antibody / FKBP133

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A19-D1210) was used as the immunogen for the FKBP15 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FKBP15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FKBP15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Alternative Name: FKBP15

Background: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interactome