Aquaporin 4 antibody (AA 200-323)

Catalog No. ABIN7871965

The Mouse Monoclonal anti-Aquaporin 4 antibody (Clone AQP4-3321) (ABIN7871965) specifically detects Aquaporin 4 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Aquaporin 4 antibody (AA 200-323) (ABIN7871965)

Target: Aquaporin 4 (AQP4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AQP4-3321

Product Details anti-Aquaporin 4 Antibody

Binding Specificity: AA 200-323

Purpose: Aquaporin 4 Antibody / AQP4

Purification: Protein G affinity

Immunogen: A human partial recombinant protein (from within amino acids 200-323) was used as the immunogen for the Aquaporin 4 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Aquaporin 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the Aquaporin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: Aquaporin 4

Background: In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

UniProt: P55087

Pathways: Sensory Perception of Sound