MCCC2 antibody (AA 21-330)

Catalog No. ABIN7872164

This Rabbit Polyclonal antibody specifically detects MCCC2 in WB, ELISA, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MCCC2 antibody (AA 21-330) (ABIN7872164)

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MCCC2 Antibody

Binding Specificity: AA 21-330

Purpose: MCCC2 Antibody / Methylcrotonoyl-CoA carboxylase beta chain

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids R21-D330) was used as the immunogen for the MCCC2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MCCC2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MCCC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2

Background: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: Q9HCC0