FGFR2 antibody (AA 22-821)

Catalog No. ABIN7872337

The Rabbit Polyclonal anti-FGFR2 antibody (ABIN7872337) specifically detects FGFR2 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for FGFR2 antibody (AA 22-821) (ABIN7872337)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-FGFR2 Antibody

Binding Specificity: AA 22-821

Purpose: Fibroblast growth factor receptor 2 Antibody / FGFR2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R22-T821) was used as the immunogen for the Fibroblast growth factor receptor 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fibroblast growth factor receptor 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Fibroblast growth factor receptor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Alternative Name: Fibroblast growth factor receptor 2

Background: Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.

UniProt: P21802

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding