STEAP2 antibody (AA 229-258)

Catalog No. ABIN7872430

The Rabbit Polyclonal anti-STEAP2 antibody (ABIN7872430) specifically detects STEAP2 in WB, IHC (p) and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for STEAP2 antibody (AA 229-258) (ABIN7872430)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-STEAP2 Antibody

Binding Specificity: AA 229-258

Purpose: STEA2 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 229-258 from the human protein was used as the immunogen for the STEA2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the STEA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the STEA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Alternative Name: STEA2

Background: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis