CDC25C antibody (AA 24-447)

Catalog No. ABIN7872694

The Rabbit Polyclonal anti-CDC25C antibody (ABIN7872694) specifically detects CDC25C in WB. The antibody is reactive with Rat samples.

Quick Overview for CDC25C antibody (AA 24-447) (ABIN7872694)

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC25C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC25C Antibody

Binding Specificity: AA 24-447

Purpose: Cdc25c Antibody

Purification: Affinity purified

Immunogen: A mouse recombinant partial protein (amino acids K24-Q447) was used as the immunogen for the Cdc25c antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cdc25c antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cdc25c antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CDC25C

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Alternative Name: Cdc25c

Background: M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

UniProt: P48967

Pathways: Cell Division Cycle, M Phase