RP2 antibody (AA 244-348)

Catalog No. ABIN7872775

The Mouse Monoclonal anti-RP2 antibody (Clone 3D7) (ABIN7872775) specifically detects RP2 in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for RP2 antibody (AA 244-348) (ABIN7872775)

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3D7

Product Details anti-RP2 Antibody

Binding Specificity: AA 244-348

Purpose: RP2 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids D244-M348) was used as the immunogen for the RP2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the RP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death.The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process