Recombinant EPO antibody (AA 28-162)

Catalog No. ABIN7873231

The Rabbit Monoclonal anti-EPO antibody (Clone EPO-3793R) (ABIN7873231) specifically detects EPO in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant EPO antibody (AA 28-162) (ABIN7873231)

Target: EPO (Erythropoietin (EPO))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EPO-3793R

Product Details anti-EPO Antibody

Binding Specificity: AA 28-162

Purpose: Recombinant EPO Antibody / Erythropoietin

Purification: Protein A affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 28-162) was used as the immunogen for the recombinant EPO antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant EPO antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant EPO antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: EPO

Target Type: Hormone

Background: Recognizes a protein of about 37 kDa, which is identified as Erythropoietin (EPO). Erythropoietin is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.

UniProt: P01588

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity