EYA4 antibody (AA 28-205)
Quick Overview for EYA4 antibody (AA 28-205) (ABIN7873244)
Target
See all EYA4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 28-205
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Purpose
- EYA4 Antibody
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Purification
- Affinity purified
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Immunogen
- Recombinant human protein (amino acids R28-E205) was used as the immunogen for the EYA4 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the EYA4 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the EYA4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EYA4 (Eyes Absent Homolog 4 (EYA4))
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Alternative Name
- EYA4
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Background
- This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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UniProt
- O95677
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Pathways
- Sensory Perception of Sound
Target
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