Poliovirus Receptor antibody (AA 28-331)

Catalog No. ABIN7873258

The Mouse Monoclonal anti-Poliovirus Receptor antibody (Clone 3B11E9) (ABIN7873258) specifically detects Poliovirus Receptor in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Poliovirus Receptor antibody (AA 28-331) (ABIN7873258)

Target: Poliovirus Receptor (PVR)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3B11E9

Product Details anti-Poliovirus Receptor Antibody

Binding Specificity: AA 28-331

Purpose: Poliovirus Receptor Antibody / PVR

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D28-E331) was used as the immunogen for the Poliovirus Receptor antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Poliovirus Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Poliovirus Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: Poliovirus Receptor

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome