The Rabbit Polyclonal anti-Thrombomodulin antibody (ABIN7873432) specifically detects Thrombomodulin in WB, ELISA, IP, FACS, IF and IHC (p).
The antibody is reactive with Human and Rat samples.
THBD
Reactivity: Human
WB, FACS, IF
Host: Rabbit
Polyclonal
RB56919
unconjugated
Application Notes
Optimal dilution of the Thrombomodulin antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Thrombomodulin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Thrombomodulin (THBD)
Alternative Name
Thrombomodulin
Background
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.