Paired Box 3 antibody (AA 301-479)

Catalog No. ABIN7873707

The Rabbit Polyclonal anti-Paired Box 3 antibody is suitable to detect Paired Box 3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for Paired Box 3 antibody (AA 301-479) (ABIN7873707)

Target: Paired Box 3 (PAX3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Paired Box 3 Antibody

Binding Specificity: AA 301-479

Purpose: PAX3 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids T301-F479) was used as the immunogen for the PAX3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PAX3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PAX3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation