CD82 antibody (AA 32-266)

Catalog No. ABIN7873913

This Rabbit Polyclonal antibody specifically detects CD82 in ELISA, FACS and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for CD82 antibody (AA 32-266) (ABIN7873913)

Target: CD82

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD82 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD82 Antibody

Binding Specificity: AA 32-266

Purpose: Cd82 Antibody

Purification: Affinity purified

Immunogen: Recombinant mouse protein (amino acids V32-Y266) was used as the immunogen for the Cd82 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cd82 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cd82 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CD82

Target: CD82

Alternative Name: Cd82

Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

UniProt: P40237

Pathways: p53 Signaling