Glypican 3 antibody (AA 32-535)

Catalog No. ABIN7873927

The Rabbit Polyclonal anti-Glypican 3 antibody (ABIN7873927) specifically detects Glypican 3 in WB, FACS and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Glypican 3 antibody (AA 32-535) (ABIN7873927)

Target: Glypican 3 (GPC3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glypican 3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-Glypican 3 Antibody

Binding Specificity: AA 32-535

Purpose: Glypican 3 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids D32-A535) was used as the immunogen for the Glypican 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Glypican 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Glypican 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Glypican 3

Target: Glypican 3 (GPC3)

Alternative Name: Glypican 3

Background: Glypican-3 is a protein that, in humans, is encoded by the GPC3 gene. It is mapped to Xq26.2. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process