FOLR1 antibody (AA 33-68)

Catalog No. ABIN7874012

This Rabbit Polyclonal antibody specifically detects FOLR1 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FOLR1 antibody (AA 33-68) (ABIN7874012)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOLR1 Antibody

Binding Specificity: AA 33-68

Purpose: Folate Receptor alpha Antibody / FOLR1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 33-68 from the human protein was used as the immunogen for the Folate Receptor alpha antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Folate Receptor alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Folate Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: Folate Receptor alpha

Background: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

UniProt: P15328

Pathways: Dicarboxylic Acid Transport