FOXN1 antibody (AA 350-378)

Catalog No. ABIN7874182

The Rabbit Polyclonal anti-FOXN1 antibody (ABIN7874182) specifically detects FOXN1 in WB. The antibody is reactive with Human samples.

Quick Overview for FOXN1 antibody (AA 350-378) (ABIN7874182)

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXN1 Antibody

Binding Specificity: AA 350-378

Purpose: FOXN1 Antibody / Forkhead box protein N1

Immunogen: A portion of amino acids 350-378 from the human protein was used as the immunogen for this FOXN1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FOXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the FOXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXN1

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Alternative Name: FOXN1

Background: FOXN1 is a member of the forkhead box (FOX) family of transcription factors, which play key roles in regulating gene expression. FOXN1 is primarily known for its critical function in the development and maintenance of the thymus, a crucial organ of the immune system. This protein is essential for the differentiation and maturation of thymic epithelial cells, which in turn support the development of T cells, a vital component of the adaptive immune response. Mutations in the FOXN1 gene have been linked to a rare genetic condition known as T-cell lymphopenia, where individuals have decreased levels of T cells and are more susceptible to infections. In addition to its role in immune function, FOXN1 has also been investigated for its potential in regenerative medicine. Studies have shown that FOXN1 expression is crucial for the regeneration of hair follicles and skin in mammals.

UniProt: O15353