RYR2 antibody (AA 3506-3540)

Catalog No. ABIN7874223

The Rabbit Polyclonal anti-RYR2 antibody is suitable to detect RYR2 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for RYR2 antibody (AA 3506-3540) (ABIN7874223)

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-RYR2 Antibody

Binding Specificity: AA 3506-3540

Purpose: Ryanodine receptor 2 Antibody / RYR2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R3506-D3540) was used as the immunogen for the Ryanodine receptor 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ryanodine receptor 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Ryanodine receptor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Alternative Name: Ryanodine receptor 2

Background: Ryanodine receptor 2 (RYR2) is a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2 gene. This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction