Recombinant STAR antibody (AA 39-108)

Catalog No. ABIN7874557

The Rabbit Monoclonal anti-STAR antibody (Clone STAR-3915R) (ABIN7874557) specifically detects STAR in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant STAR antibody (AA 39-108) (ABIN7874557)

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STAR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: STAR-3915R

Product Details anti-STAR Antibody

Binding Specificity: AA 39-108

Purpose: Recombinant StAR Antibody / Steroidogenic acute regulatory protein (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 39-108 was used as the immunogen for the recombinant StAR antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant StAR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant StAR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for STAR

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Alternative Name: StAR

Background: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

UniProt: P49675

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis