DENND1B antibody (AA 39-68)

Catalog No. ABIN7874606

This Rabbit Polyclonal antibody specifically detects DENND1B in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DENND1B antibody (AA 39-68) (ABIN7874606)

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DENND1B Antibody

Binding Specificity: AA 39-68

Purpose: DENND1B Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the DENND1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DENND1B

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Alternative Name: DENND1B

Background: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

UniProt: Q6P3S1