DDX21 antibody (AA 395-660)

Catalog No. ABIN7874638

The Rabbit Polyclonal anti-DDX21 antibody (ABIN7874638) specifically detects DDX21 in WB, IF, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for DDX21 antibody (AA 395-660) (ABIN7874638)

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX21 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Product Details anti-DDX21 Antibody

Binding Specificity: AA 395-660

Purpose: DDX21 Antibody / Nucleolar RNA helicase 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E395-Q660) was used as the immunogen for the DDX21 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DDX21 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DDX21 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DDX21

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Alternative Name: DDX21

Background: Nucleolar RNA helicase 2 is an enzyme that in humans is encoded by the DDX21 gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

UniProt: Q9NR30

Pathways: SARS-CoV-2 Protein Interactome