Glutaminase antibody (AA 396-654)

Catalog No. ABIN7874646

The Mouse Monoclonal anti-Glutaminase antibody is suitable to detect Glutaminase in samples from Human, Mouse and Rat. It has been validated for WB, IF and IHC (p).

Quick Overview for Glutaminase antibody (AA 396-654) (ABIN7874646)

Target: Glutaminase (GLS)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutaminase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 9G6

Product Details anti-Glutaminase Antibody

Binding Specificity: AA 396-654

Purpose: Glutaminase Antibody / GLS

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids K396-N654) was used as the immunogen for the Glutaminase antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Glutaminase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Glutaminase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Glutaminase

Target: Glutaminase (GLS)

Alternative Name: Glutaminase

Background: This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect