MTHFD1L antibody (AA 43-833)

Catalog No. ABIN7874976

The Rabbit Polyclonal anti-MTHFD1L antibody is suitable to detect MTHFD1L in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for MTHFD1L antibody (AA 43-833) (ABIN7874976)

Target: MTHFD1L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTHFD1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MTHFD1L Antibody

Binding Specificity: AA 43-833

Purpose: Monofunctional C1-tetrahydrofolate synthase Antibody / MTHFD1L

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R43-V833) was used as the immunogen for the Monofunctional C1-tetrahydrofolate synthase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Monofunctional C1-tetrahydrofolate synthase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Monofunctional C1-tetrahydrofolate synthase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MTHFD1L

Target: MTHFD1L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L))

Alternative Name: Monofunctional C1-tetrahydrofolate synthase

Background: Monofunctional C1-tetrahydrofolate synthase, mitochondrial also known as formyltetrahydrofolate synthetase, is an enzyme that in humans is encoded by the MTHFD1L gene (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like). The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: Q6UB35