Fibronectin 1 antibody (AA 467-595)

Catalog No. ABIN7875152

This Mouse Monoclonal antibody specifically detects Fibronectin 1 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Fibronectin 1 antibody (AA 467-595) (ABIN7875152)

Target: Fibronectin 1 (FN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FN1-3569

Product Details anti-Fibronectin 1 Antibody

Binding Specificity: AA 467-595

Purpose: Fibronectin 1 Antibody / FN1

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 467-595 was used as the immunogen for the Fibronectin 1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Fibronectin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Fibronectin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: Fibronectin 1

Background: Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy