Fibronectin 1 antibody (AA 467-595)

Catalog No. ABIN7875154

The Mouse Monoclonal anti-Fibronectin 1 antibody (Clone FN1-2948) (ABIN7875154) specifically detects Fibronectin 1 in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Fibronectin 1 antibody (AA 467-595) (ABIN7875154)

Target: Fibronectin 1 (FN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FN1-2948

Product Details anti-Fibronectin 1 Antibody

Binding Specificity: AA 467-595

Purpose: FN1 Antibody / Fibronectin

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 467-595 from the human protein was used as the immunogen for the FN1 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the FN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the FN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: FN1

Background: Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy