AXL antibody (AA 47-244)

Catalog No. ABIN7875158

This Rabbit Polyclonal antibody specifically detects AXL in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for AXL antibody (AA 47-244) (ABIN7875158)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-AXL Antibody

Binding Specificity: AA 47-244

Purpose: AXL Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids A47-A244) was used as the immunogen for the AXL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AXL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the AXL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL

Background: Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. This gene is mapped to 19q13.2. The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin