SOX18 antibody (AA 50-250)

Catalog No. ABIN7875394

The Mouse Monoclonal anti-SOX18 antibody (Clone SOX18-3271) (ABIN7875394) specifically detects SOX18 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for SOX18 antibody (AA 50-250) (ABIN7875394)

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX18 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SOX18-3271

Product Details anti-SOX18 Antibody

Binding Specificity: AA 50-250

Purpose: SOX18 Antibody

Purification: Protein A/G affinity

Immunogen: A recombinant human SOX18 protein fragment (within amino acids 50-250) was used as the immunogen for the SOX18 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the SOX18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SOX18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Alternative Name: SOX18

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

UniProt: P35713