FANCC antibody (AA 527-555)

Catalog No. ABIN7875586

The Rabbit Polyclonal anti-FANCC antibody (ABIN7875586) specifically detects FANCC in WB, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FANCC antibody (AA 527-555) (ABIN7875586)

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FANCC Antibody

Binding Specificity: AA 527-555

Purpose: FANCC Antibody / Fanconi anemia group C protein

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 527-555 from the human protein was used as the immunogen for the FANCC antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FANCC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FANCC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.

UniProt: Q00597

Pathways: DNA Damage Repair