Thrombomodulin antibody (AA 537-571)

Catalog No. ABIN7875612

The Rabbit Polyclonal anti-Thrombomodulin antibody is suitable to detect Thrombomodulin in samples from Human. It has been validated for WB.

Quick Overview for Thrombomodulin antibody (AA 537-571) (ABIN7875612)

Target: Thrombomodulin (THBD)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 537-571

Purpose: Thrombomodulin Antibody (C-Terminal Region)

Purification: Antigen affinity

Immunogen: A portion of amino acids 537-571 from human THBD was used as the immunogen for the Thrombomodulin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: Thrombomodulin

Background: Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]

UniProt: P07204