MMP2 antibody (AA 557-569)

Catalog No. ABIN7875726

The Mouse Monoclonal anti-MMP2 antibody is suitable to detect MMP2 in samples from Human. It has been validated for IHC (p).

Quick Overview for MMP2 antibody (AA 557-569) (ABIN7875726)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: 4D3

Product Details anti-MMP2 Antibody

Binding Specificity: AA 557-569

Purpose: MMP2 Antibody / Matrix metalloproteinase 2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant human MMP2 protein fragment (within amino acids 557-569) was used as the immunogen for the MMP2 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the MMP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the MMP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: MMP2

Background: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

UniProt: P08253

Pathways: Activation of Innate immune Response