Recombinant alpha Sarcomeric Actin (AA 557-692) antibody
The Rabbit Monoclonal anti-alpha Sarcomeric Actin antibody (Clone ACTN2-7041R) (ABIN7875745) specifically detects alpha Sarcomeric Actin in IHC (p).
The antibody is reactive with Human samples.
Catalog No. ABIN7875745
$640.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Recombinant alpha Sarcomeric Actin (AA 557-692) antibody (ABIN7875745)
Target
alpha Sarcomeric Actin
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Un-conjugated
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Grade
Carrier-free
Clone
ACTN2-7041R
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Binding Specificity
- AA 557-692
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Purpose
- Recombinant Sarcomeric Alpha Actinin Antibody / Alpha Actinin 2 / ACTN2 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- A portion of amino acids 557-692 from the human protein was used as the immunogen for the recombinant Sarcomeric Alpha Actinin antibody.
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Isotype
- IgG, kappa
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anti-alpha Sarcomeric Actin antibody
Reactivity: Mouse, Rat WB, IHC, EM, IF Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal dilution of the recombinant Sarcomeric Alpha Actinin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Handling Advice
- Avoid repeated freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Aliquot the recombinant Sarcomeric Alpha Actinin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- alpha Sarcomeric Actin
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Alternative Name
- Sarcomeric Alpha Actinin
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Background
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P35609
Target
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