Calnexin antibody (AA 560-592)
Quick Overview for Calnexin antibody (AA 560-592) (ABIN7875783)
Target
See all Calnexin (CANX) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 560-592
-
Purpose
- Calnexin Antibody (C-Terminal Region)
-
Purification
- Antigen affinity
-
Immunogen
- A portion of amino acids 560-592 from human Calnexin was used as the immunogen for the Calnexin antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Aliquot the Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Calnexin (CANX)
-
Alternative Name
- Calnexin
-
Background
- Calnexin is a calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. [UniProt]
-
UniProt
- P27824
-
Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
Target
-