LINGO1 antibody (AA 575-603)

Catalog No. ABIN7875827

This Rabbit Polyclonal antibody specifically detects LINGO1 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for LINGO1 antibody (AA 575-603) (ABIN7875827)

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LINGO1 Antibody

Binding Specificity: AA 575-603

Purpose: Lingo1 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 575-603 from the mouse protein was used as the immunogen for the Lingo1 Antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Lingo1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Lingo1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: Lingo1

Background: Leucine-rich repeat and immunoglobulin domain-containing protein 1' is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. [UniProt]

UniProt: Q9D1T0