beta Amyloid antibody (AA 578-680)

Catalog No. ABIN7875832

The Mouse Monoclonal anti-beta Amyloid antibody (Clone APP-3343) (ABIN7875832) specifically detects beta Amyloid in IHC (p). The antibody is reactive with Human samples.

Quick Overview for beta Amyloid antibody (AA 578-680) (ABIN7875832)

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Amyloid antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: APP-3343

Product Details anti-beta Amyloid Antibody

Binding Specificity: AA 578-680

Purpose: Beta Amyloid Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 578-680 from the human protein was used as the immunogen for the Beta Amyloid antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Beta Amyloid antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Beta Amyloid antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Alternative Name: Beta Amyloid

Background: Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.

UniProt: P05067

Pathways: Inflammasome