NCOR2 antibody (AA 6-2148)

Catalog No. ABIN7875945

The Rabbit Polyclonal anti-NCOR2 antibody is suitable to detect NCOR2 in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for NCOR2 antibody (AA 6-2148) (ABIN7875945)

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-NCOR2 Antibody

Binding Specificity: AA 6-2148

Purpose: NCOR2 Antibody / Nuclear receptor corepressor 2 / SMRT

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q6-H2148) was used as the immunogen for the NCOR2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NCOR2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NCOR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Alternative Name: NCOR2

Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9Y618

Pathways: Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha