SREBF chaperone antibody (AA 604-632)

Catalog No. ABIN7876074

The Rabbit Polyclonal anti-SREBF chaperone antibody is suitable to detect SREBF chaperone in samples from Human, Mouse and Rat. It has been validated for WB, FACS, IHC (p) and IF.

Quick Overview for SREBF chaperone antibody (AA 604-632) (ABIN7876074)

Target: SREBF chaperone (SCAP)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SREBF chaperone Antibody

Binding Specificity: AA 604-632

Purpose: SCAP Antibody / SREBP cleavage-activating protein

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 604-632 from the human protein were used as the immunogen for the SCAP antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SCAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SCAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background: SCAP is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome