PREX1 antibody (AA 643-1155)

Catalog No. ABIN7876266

The Rabbit Polyclonal anti-PREX1 antibody is suitable to detect PREX1 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for PREX1 antibody (AA 643-1155) (ABIN7876266)

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PREX1 Antibody

Binding Specificity: AA 643-1155

Purpose: PREX1 Antibody

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids N643-D1155) was used as the immunogen for the PREX1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PREX1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PREX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Alternative Name: PREX1

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein is a protein that in humans is encoded by the PREX1 gene. The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization