Integrin Alpha2b antibody (AA 675-714)

Catalog No. ABIN7876394

This Rabbit Polyclonal antibody specifically detects Integrin Alpha2b in FACS, WB, ELISA and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for Integrin Alpha2b antibody (AA 675-714) (ABIN7876394)

Target: Integrin Alpha2b (CD41)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Integrin Alpha2b Antibody

Binding Specificity: AA 675-714

Purpose: ITGA2B Antibody / Integrin alpha 2b

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A675-R714) was used as the immunogen for the ITGA2B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ITGA2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ITGA2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Background: Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

UniProt: P08514

Pathways: Integrin Complex