TTR antibody (AA 71-98)

Catalog No. ABIN7876613

This Rabbit Polyclonal antibody specifically detects TTR in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TTR antibody (AA 71-98) (ABIN7876613)

Target: TTR (Transthyretin (TTR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TTR Antibody

Binding Specificity: AA 71-98

Purpose: Transthyretin Antibody / TTR / Prealbumin

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 71-98 from the human protein was used as the immunogen for the Transthyretin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Transthyretin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Transthyretin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TTR

Target: TTR (Transthyretin (TTR))

Alternative Name: Transthyretin

Background: Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

UniProt: P02766

Pathways: Hormone Transport