EIF3C antibody (AA 81-637)

Catalog No. ABIN7876897

The Rabbit Polyclonal anti-EIF3C antibody (ABIN7876897) specifically detects EIF3C in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EIF3C antibody (AA 81-637) (ABIN7876897)

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EIF3C Antibody

Binding Specificity: AA 81-637

Purpose: EIF3C Antibody / Eukaryotic translation initiation factor 3 subunit C

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E81-Q637) was used as the immunogen for the EIF3C antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EIF3C antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the EIF3C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EIF3C

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Alternative Name: EIF3C

Background: Eukaryotic translation initiation factor 3 subunit C (eIF3c) is a protein that in humans is encoded by the EIF3C gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization