MDH2
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
2A7
unconjugated
Application Notes
Optimal dilution of the Malate dehydrogenase 2 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Malate dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
MDH2
(Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2))
Alternative Name
Malate dehydrogenase 2
Background
Malate dehydrogenase, mitochondrial, also known as malate dehydrogenase 2, is an enzyme that in humans is encoded by the MDH2 gene. Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.