MAP2K5 antibody (AA 9-442)

Catalog No. ABIN7877086

The Rabbit Polyclonal anti-MAP2K5 antibody (ABIN7877086) specifically detects MAP2K5 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MAP2K5 antibody (AA 9-442) (ABIN7877086)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MAP2K5 Antibody

Binding Specificity: AA 9-442

Purpose: MEK5 Antibody / MAP2K5

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids F9-R442) was used as the immunogen for the MEK5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MEK5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MEK5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: MEK5

Background: Dual specificity mitogen-activated protein kinase kinase 5 is an enzyme that in humans is encoded by the MAP2K5 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

UniProt: Q13163

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway