PPP1R13B antibody (AA 901-1090)

Catalog No. ABIN7877127

The Rabbit Polyclonal anti-PPP1R13B antibody is suitable to detect PPP1R13B in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PPP1R13B antibody (AA 901-1090) (ABIN7877127)

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPP1R13B Antibody

Binding Specificity: AA 901-1090

Purpose: ASPP1 Antibody / PPP1R13B

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (F901-A1090) was used as the immunogen for the ASPP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ASPP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ASPP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Alternative Name: ASPP1

Background: Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

UniProt: Q96KQ4

Pathways: p53 Signaling