Recombinant Transferrin Receptor antibody (Extracellular)

Catalog No. ABIN7877191

The Rabbit Monoclonal anti-Transferrin Receptor antibody (Clone TFRC-2898R) (ABIN7877191) specifically detects Transferrin Receptor in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Transferrin Receptor antibody (Extracellular) (ABIN7877191)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: TFRC-2898R

Product Details anti-Transferrin Receptor Antibody

Binding Specificity: AA 94-212, Extracellular

Purpose: Recombinant CD71 Antibody / Transferrin Receptor / TFRC (Extracellular domain) (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: A recombinant human partial protein (extracellular region, amino acids 94-212) was used as the immunogen for this recombinant CD71 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant CD71 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71

Background: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis